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KMID : 0882420080750000889
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Korean Journal of Medicine
2008 Volume.75 No. 0 p.889 ~ p.893
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Hypermagnesemia induced by massive cathartic ingestion
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Kwak Jin-Ho
Kang Gun-Woo
Kwon Jeong-Seok
Shin Young-Kook
Kim Myung-Hwan
Lee In-Hee
Ahn Ki-Sung
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Abstract
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Hypermagnesemia is a rare laboratory finding and is easily neglected. Symptomatic hypermagnesemia is mainly iatrogenic, occurring after intravenous magnesium administration or the oral ingestion of magnesium-containing cathartics or antacids. The elderly and patients with bowel disorders or renal insufficiency are at high risk, and marked hypermagnesemia is a serious, often fatal condition in these patients. A 71-year-old man was referred to our hospital for hypotension, refractory to catecholamine. He had already received 21g of magnesium hydroxide orally for two days. He was lethargic, and his systolic blood pressure was less than 80 mmHg. The serum magnesium concentration was elevated to 5.85 mg/dL. On the sixth hospital day, his hypermagnesemia improved with intravenous calcium, inotropics, and saline infusion, but he remained in respiratory depression and ileus until the serum magnesium concentration was lowered to less than 2.2 mg/dL. Unfortunately, on the twelfth hospital day, he died from ventilatory-associated pneumonia and ventricular tachycardia. (Korean J Med 75:S889-S893, 2008)
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KEYWORD
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Magnesium, Magnesium hydroxide, Cathartic
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